Main Article Content
Background and objectives
The coronavirus disease 2019 (COVID-19) pandemic is having a significant impact on healthcare delivery. As a result, management of patients with ureteric stones has likely been affected. We report our study protocol for the investigation of ureteric stone management during and after the COVID-19 pandemic.
Material and methods
The COVID Stones study is a multicenter national cohort study of the management and outcomes of patients with ureteric stones before, during, and after the COVID-19 pandemic in the United Kingdom. The study will consist of three data collection periods, pre-pandemic (“pre-COVID”), pandemic (“COVID”), and post-pandemic (“post-COVID”). This will allow quantification of what “normal” was, how this has changed, and to capture any persisting changes in management. The primary outcome evaluating the success rate of the initial treatment decision will be assessed following a 6-month follow-up from the time of first presentation and will be performed for each recruited patient from each of the three data collection periods. This will allow comparison between both management and outcomes before, during, and after the pandemic.
We anticipate that this study will lead to an increased understanding of the impact of the outcomes of emergency management of ureteric stones following changes in clinical practice due to the COVID-19 pandemic health provision restrictions.
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2. Scales CD Jr, Smith AC, Hanley JM, Saigal CS; Urologic Diseases in America Project. Prevalence of kidney stones in the United States. Eur Urol 2012;62(1):160–5. http://dx.doi.org/10.1016/j.eururo.2012.03.052
3. Geraghty RM, Cook P, Walker V, Somani BK. Evaluation of the economic burden of kidney stone disease in the UK: A retrospective cohort study with a mean follow-up of 19 years. BJU Int 2020;125(4):586–94. http://dx.doi.org/10.1111/bju.14991
4. Shah TT, Gao C, Peters M, et al. Factors associated with spontaneous stone passage in a contemporary cohort of patients presenting with acute ureteric colic: Results from the multi-centre cohort study evaluating the role of inflammatory markers in patients presenting with acute ureteric Colic (MIMIC) study. BJU Int 2019;124(3):504–13. http://dx.doi.org/10.1111/ bju.14777
5. Pearle MS, Pierce HL, Miller GL, et al. Optimal method of urgent decompression of the collecting system for obstruction and infection due to ureteral calculi. J Urol 1998;160(4):1260–4. http://dx.doi.org/10.1016/ S0022-5347(01)62511-4
6. NICE guideline NG118: Renal and ureteric stones: Assessment and management. 2019. https://www.nice. org.uk/guidance/ng118 (accessed on: July 16, 2020).
7. Zhou F, Yu T, Du R, et al. Clinical course and risk fac-tors for mortality of adult inpatients with COVID-19 in Wuhan, China: A retrospective cohort study. Lancet 2020;395:1054–62. http://dx.doi.org/10.1016/ S0140-6736(20)30566-3
8. Cucinotta D, Vanelli M. WHO declares COVID-19 a pandemic. Acta Biomed 2020;91:157–60.
9. COVIDSurg Collaborative. Elective surgery cancellations due to the COVID-19 pandemic: Global predictive modelling to inform surgical recovery plans [published online ahead of print, 2020 May 12]. Br J Surg 2020. http://dx.doi.org/10.1002/bjs.11746
10. COVIDSurg Collaborative. Mortality and pulmonary complications in patients undergoing surgery with perioperative SARS-CoV-2 infection: An international cohort study [published correction appears in Lancet 2020 Jun 9]. Lancet 2020;396(10243):27–38. http:// dx.doi.org/10.1016/S0140-6736(20)31182-X
11. Royal College of Surgeons of England. Updated Inter-collegiate General Surgery Guidance on COVID-19. London: Royal College of Surgeons of England, 2020. https://www.rcseng.ac.uk/coronavirus/joint-guidance-for-surgeons-v2/ (accessed on: July 17, 2020).
12. Thornton J. Covid-19: A&E visits in England fall by 25% in week after lockdown. BMJ 2020;369:m1401. http://dx.doi.org/10.1136/bmj.m1401
13. Harris PA, Taylor R, Thielke R, et al. Research electronic data capture (REDCap) – A metadata-driven methodology and workflow process for providing translational research informatics support. J Biomed Inform 2009;42(2):377–81. http://dx.doi.org/10.1016/j. jbi.2008.08.010
14. Harris PA, Taylor R, Minor BL, et al. The REDCap con-sortium: Building an international community of software platform partners. J Biomed Inform 2019;95:103208. http://dx.doi.org/10.1016/j.jbi.2019.103208
15. Javanmard-Emamghissi H, Boyd-Carson H, Hollyman M, et al. The management of adult appendicitis during the COVID-19 pandemic: An interim analysis of a UK cohort study [published online ahead of print, 2020 Jul 15]. Tech Coloproctol 2020;1–11. http://dx.doi. org/10.1007/s10151-020-02297-4
16. CHOLECOVID Collaborative. CHOLECOVID study protocol. 2020. https://cholecovid.org/ (accessed on: July 21, 2020).
17. Proietti S, Gaboardi F, Giusti G. Endourological stone management in the era of the COVID-19 [published online ahead of print, 2020 Apr 14]. Eur Urol 2020;S0302-2838(20)30217-7. http://dx.doi. org/10.1016/j.eururo.2020.03.042
18. Metzler IS, Sorensen MD, Sweet RM, Harper JD. Stone care triage during COVID-19 at the University of Washington. J Endourol 2020;34(5):539–40. http:// dx.doi.org/10.1089/end.2020.29080.ism
19. Stensland KD, Morgan TM, Moinzadeh A, et al. Con-siderations in the triage of urologic surgeries during the COVID-19 pandemic. Eur Urol 2020;77(6):663–6. http://dx.doi.org/10.1016/j.eururo.2020.03.027
20. Gökce Mİ, Yin S, Sönmez MG, et al. How does the COVID-19 pandemic affect the preoperative evaluation and anesthesia applied for urinary stones? EU-LIS eCORE-IAU multicenter collaborative cohort study. Urolithiasis 2020;48(4):345–51. http://dx.doi. org/10.1007/s00240-020-01193-8
21. Flammia S, Salciccia S, Tufano A, et al. How urinary stone emergencies changed in the time of COVID-19? [published online ahead of print, 2020 May 28]. Urolithiasis 2020;1–3. http://dx.doi.org/10.1007/ s00240-020-01198-3